The molecule occurs naturally in the human body. It is a native human peptide or protein rather than an analogue or a modified version. The field states where the sequence comes from biologically, not how the material in a vial was made. The body typically produces these in very small amounts, released in patterns and under feedback control.

Why it matters here

Endogenous status is often used as reassurance on product pages. On a record it changes nothing about the evidence rung, because a graded claim depends on what was studied and at what exposure, not on whether the molecule is already familiar to the body.

Also called

• human endogenous
• endogenous
• naturally occurring
• human native

Naturally occurring and human native are the plain-English forms. Endogenous used alone is ambiguous in the literature, which sometimes applies it to other species.

Compounds carrying this term

None on file yet. This term is in the controlled vocabulary but no compound record currently uses it — which is a statement about our coverage, not about the term.

See also

• Synthetic — Molecular Origin
• Recombinant — Molecular Origin