Delivery through intact skin with the aim of reaching the bloodstream and acting elsewhere in the body. Molecules that manage this reliably tend to be small and fat-soluble, which describes very few peptides. A patch is the usual form, because it holds a controlled concentration against the skin for hours at a time.

Why it matters here

This is the route where the gap between intent and measurement is widest, so it is worth checking what a record's evidence rung actually measured: a plasma concentration is transdermal evidence, and a skin-surface or laboratory diffusion result is not.

Also called

• transdermal
• patch

Patch is a dosage form rather than a route, indexed here because it is the word people search for.

Compounds carrying this term

None on file yet. This term is in the controlled vocabulary but no compound record currently uses it — which is a statement about our coverage, not about the term.

See also

• Topical — Route of Administration
• DMSO — Vehicle / Diluent
• Cream or Gel Base — Vehicle / Diluent