Tissue Repair & Regeneration

Acetyl Tetrapeptide-11

Last updated 12 August 2026

Evidence on file2 in-vitro studies · 2 citations not yet graded

Strongest sourceCombinations of peptides synergistically activate the regenerative capacity of skin cells in vitro. (in-vitro study)

Manufacturer’s claim vendor marketing

For a proprietary cosmetic ingredient the manufacturer is the originator — there is no upstream to defer to, and this is often the only description that exists. It is reproduced as an attributed claim, with the label its source gave it. It is not graded and it is not evidence — the graded studies are under Literature.

Vendor claim quoted from fetched SpecialChem/BASF product page: "offers improvement of skin appearance and firmness"; "suitable for anti-age face care, specific care for mature skin and radiant senior skin care formulations". No n= or duration on fetched pages.

Manufacturer: BASF
Sold as: SYNIORAGE (SYNIORAGE LS 9748; also SYNIORAGE PW LS 9847)
Manufacturer’s recommended use: Not provided on fetched pages

Source page — nofollow, because a vendor link is a reference here, not an endorsement.

Dosing on file unverified

0.1-3% in creams; 0.1-0.5% for skin tightening

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 4

in vitro
Combinations of peptides synergistically activate the regenerative capacity of skin cells in vitro. graded on: an in-vitro system — “in vitro”
in vitro
Hydrodynamically generated multilayer skin spheroids enable in vitro screening of biologically active ingredients and toxicity tests. graded on: an in-vitro system — “in vitro”

Not graded

2 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

Space-filling 3D model of Acetyl Tetrapeptide-11, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Acetyl Tetrapeptide-11 — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 530.6
Molecular formula: C27H38N4O7
CAS number: 928006-88-6
PubChem CID: 91936941
InChI key: KQEQPUBSXXOUGC-MLCQCVOFSA-N
SMILES: CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)C
InChI: InChI=1S/C27H38N4O7/c1-16(2)14-21(27(37)38)29-24(34)20(15-18-8-10-19(33)11-9-18)28-25(35)22-6-4-13-31(22)26(36)23-7-5-12-30(23)17(3)32/h8-11,16,20-23,33H,4-7,12-15H2,1-3H3,(H,28,35)(H,29,34)(H,37,38)/t20-,21-,22-,23-/m0/s1

Also called

Glycerin
SYNIORAGE
SYNIORAGE PW LS 9847)

Notes unverified prose

Placebo-controlled trial (>60 yrs, 3% active): significant skin thickening & firmness; 19 female volunteers trial; BASF Syniorage™; Placebo-controlled trial (>60 yrs, 3% active)

Not on file 1

1 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

amino-acid sequencenothing we hold supplies it

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.