Gastrointestinal Health; Cognitive & Neuroprotection
Cholecystokinin (CCK)
Last updated
Dosing on file unverified
CCK-8: 20 ng/kg IV bolus; 1-4 ng/kg/min IV infusion; 16.4-65.6 pmol/kg/hr; CCK-8: 1-4 ng/kg/min IV infusion; 30 pmol/kg/h; 0.02 mg/kg; Diagnostic: 1-4 ng/kg/min for gallbladder contraction
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Literature on file 9
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animal in vivo
Establishing Murine Intestinal Organoids to Study Nutrient- and Tastant-Evoked Gut Signaling. graded on: an animal model — “Murine”
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in vitro
Synthesis and in vitro evaluation of pharmacokinetically optimized 99mTc-labeled cholecystokinin-2 receptor-targeted peptides for improved SPECT imaging. graded on: an in-vitro system — “in vitro”
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human observational
NCT02445508: Effect of Bile Acid Secretion and Sequestration on GLP-1 Secretion graded on: a registered clinical study — “clinicaltrials.gov”
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human observational
NCT02497313: Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes graded on: a registered clinical study — “clinicaltrials.gov”
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human observational
NCT00308776: Effect of Cholecystokinin on Binge Eating in Bulimia Nervosa graded on: a registered clinical study — “clinicaltrials.gov”
Not graded
4 citations whose study design could not be read from the title. Left ungraded rather than guessed at.
- not graded
- not graded
- not graded
- not graded
Identity
- UniProt
- P06307 (precursor)
Also called
- Cholecystokinin (CCK) (GI)
Caveat on these identifiers
Source files disagreed on evidence tier for this peptide.
Notes unverified prose
Diagnostic use (gallbladder contraction, pancreatic function); Human infusion studies: CCK-8 1-4 ng/kg/min; 1.5 ng/kg/min in older adults; 112 ng/min for 23 min with gastric distension; Diagnostic use (Kinevac®); CCK-8 IV infusions
Not on file 8
8 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.
- molecular weightnothing we hold supplies it
- molecular formulanothing we hold supplies it
- CAS registry numbernothing we hold supplies it
- PubChem identifiernothing we hold supplies it
- amino-acid sequencenothing we hold supplies it
- SMILES stringnothing we hold supplies it
- InChInothing we hold supplies it
- InChI keynothing we hold supplies it
Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.