Tissue Repair & Regeneration

Copper Tripeptide-1

Last updated 12 August 2026

Evidence on file2 human observational studies · 4 citations not yet graded

Strongest sourceAn Open-Label Study to Assess the Efficacy and Tolerability of a Multifunctional, 10-Peptide Face and Neck Se… (human observational study)

Manufacturer’s claim vendor marketing

For a proprietary cosmetic ingredient the manufacturer is the originator — there is no upstream to defer to, and this is often the only description that exists. It is reproduced as an attributed claim, with the label its source gave it. It is not graded and it is not evidence — the graded studies are under Literature.

Vendor claims quoted from fetched page: "stimulates collagen synthesis, promoting skin elasticity and firmness while reducing the appearance of fine lines and wrinkles"; "accelerates wound healing and soothes inflammation"; "acts as a powerful antioxidant, shielding the skin from free radicals". No n= or duration on fetched page.

Manufacturer: Multiple generic suppliers (Uniproma Chemical, Spec-Chem Industry per SpecialChem); GHK-Cu is a widely genericized active
Sold as: No single original trade name confirmed; fetched trade names: SHINE+ GHK-Cu Pro and ActiTide CP (Uniproma Chemical), SilCare GHK-Cu 1001 (Spec-Chem Industry)
Manufacturer’s recommended use: Vendor claim: "0.05-1%"

Source page — nofollow, because a vendor link is a reference here, not an endorsement.

Dosing on file unverified

0.4-1% cream, 1-2x/day (8-12 weeks)

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 6

human observational
An Open-Label Study to Assess the Efficacy and Tolerability of a Multifunctional, 10-Peptide Face and Neck Serum to Address Skin Quality. graded on: indexed as a clinical trial, design not stated — “Clinical Trial”
human observational
Efficacy of Hair Mesotherapy With Biomimetic Peptides and Micronutrients in Patients With Androgenetic Alopecia: A Retrospective Observational Study graded on: an observational human design — “Retrospective”

Not graded

4 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

Space-filling 3D model of Copper Tripeptide-1, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Copper Tripeptide-1 — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 402.92
Molecular formula: C14H23CuN6O4+
CAS number: 89030-95-5
PubChem CID: 71587328
InChI key: NZWIFMYRRCMYMN-ACMTZBLWSA-M
SMILES: C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)[O-])NC(=O)CN.[Cu+2]
InChI: InChI=1S/C14H24N6O4.Cu/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);/q;+2/p-1/t10-,11-;/m0./s1

Also called

Copper Tripeptide-1

Notes unverified prose

RCT: Leyden 2002 (71 women, 12 weeks, GHK-Cu facial cream); improved fine lines, skin density; small RCTs for wound healing; Leyden 2002 RCT (67 women, 12 weeks)

Not on file 1

1 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

amino-acid sequencenothing we hold supplies it

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.