Hormonal & Sexual Health
CRH (Corticotropin-Releasing Hormone)
Last updated
Evidence on file4 human observational studies · 2 animal studies · 4 citations not yet graded
Strongest sourceNCT01673087: Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures (human observational study)
Dosing on file unverified
1 µg/kg IV (max 100 µg) bolus over 30-60 sec; Human CRH: 33, 67, 100 µg IV
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Literature on file 10
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animal in vivo
Characterization of rat hypothalamic corticotropin-releasing factor (1983, cited 184x) graded on: an animal model — “rat”
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animal in vivo
CRH expression and function in mouse uterus during early pregnancy. graded on: an animal model — “mouse”
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human observational
NCT01673087: Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures graded on: a registered clinical study — “clinicaltrials.gov”
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human observational
NCT00001180: Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency graded on: a registered clinical study — “clinicaltrials.gov”
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human observational
NCT01984177: Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence: A [11C]-(+)-PHNO PET Investigation graded on: a registered clinical study — “clinicaltrials.gov”
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human observational
NCT00666068: Effects of CRH on the Sleep in Patients With Hypopituitarism graded on: a registered clinical study — “clinicaltrials.gov”
Not graded
4 citations whose study design could not be read from the title. Left ungraded rather than guessed at.
- not graded
- not graded
- not graded
- not graded
Identity
- UniProt
- P06850 (precursor)
Notes unverified prose
Diagnostic (CRH stimulation test); Leeds Formulary
Not on file 8
8 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.
- molecular weightnothing we hold supplies it
- molecular formulanothing we hold supplies it
- CAS registry numbernothing we hold supplies it
- PubChem identifiernothing we hold supplies it
- amino-acid sequencenothing we hold supplies it
- SMILES stringnothing we hold supplies it
- InChInothing we hold supplies it
- InChI keynothing we hold supplies it
Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.