PEPTIDE CORPUS

Cognitive & Neuroprotection

Dynorphin A

Last updated

Evidence on file1 human observational study · 2 citations not yet graded
Strongest sourceNCT00000244: Effects of Dynorphin 1-13 on Heroin Addiction (human observational study)

Dosing on file unverified

Dynorphin A(1-13): up to 1,000 µg/kg IV; Well tolerated at doses up to 1,000 µg/kg

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 3

Not graded

2 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

UniProt
P01213 (precursor)

Caveat on these identifiers

P01213 (prodynorphin) is correct for Dynorphin A only; beta-endorphin derives from POMC, not this precursor.

Notes unverified prose

Human studies: 1,000 µg/kg IV well tolerated; modest effect on opiate withdrawal; negative mood effects at high dose; Human studies up to 1,000 µg/kg IV; NCT00000244

Not on file 8

8 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.