Gastrointestinal Health

Gastrin

Last updated 12 August 2026

Evidence on file5 human observational studies · 1 human case report or series · 1 animal study · 3 citations not yet graded

Strongest sourcePharmacological safety and real-world efficacy of the potassium-competitive acid blocker fexuprazan in cardio… (human observational study)

Dosing on file unverified

Pentagastrin: 6 µg/kg SC (maximal gastric stimulation); IV: 0.6-6.0 µg/kg/hr dose-response

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 10

human case series
Clinical Outcomes of Antrectomy for Patients With Multiple Type I Gastric Neuroendocrine Tumors: A Case Series. graded on: a case report or series — “Case Series”
human observational
Pharmacological safety and real-world efficacy of the potassium-competitive acid blocker fexuprazan in cardiovascular patients receiving antithrombotic therapy: a prospective cohort study (FEXGARD). graded on: an observational human design — “cohort”
animal in vivo
Canine Gastrinoma with Long-Term Survival After Primary and Repeat Surgeries Using Serial Serum Gastrin Concentrations as an Adjunctive Monitoring Marker: A Report of Two Cases. graded on: an animal model — “Canine”
human observational
NCT01909245: Islet Transplantation Using a T-Cell Depleting Immunosuppression Induction Regimen graded on: a registered clinical study — “clinicaltrials.gov”
human observational
NCT03746769: Improving Islet Transplantation Outcomes With Gastrin graded on: a registered clinical study — “clinicaltrials.gov”
human observational
NCT02184910: Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis, Intestinal Metaplasia and Gastric Cancer in Korea graded on: a registered clinical study — “clinicaltrials.gov”
human observational
NCT07060482: Diagnostic Performance of Combined Assays for Gastrin-17, Pepsinogen and Anti-helicobacter Pylori Antibodies for Diagnosing Gastric Atrophy. graded on: a registered clinical study — “clinicaltrials.gov”

Not graded

3 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

Space-filling 3D model of Gastrin, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Gastrin — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 2116.2
Molecular formula: C97H126N20O32S
CAS number: 9002-76-0
PubChem CID: 44288444
UniProt: P01350 (precursor)
InChI key: AOXOCDRNSPFDPE-UKEONUMOSA-N
Sequence: EGPWLEEEEEAYGWMDF
SMILES: C[C@H](C(=O)N[C@H](CC1=CC=C(C=C1)O)C(=O)NCC(=O)N[C@H](CC2=CNC3=CC=CC=C32)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(=O)O)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)N)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@@H]7CCCN7C(=O)CNC(=O)[C@H](CCC(=O)O)N
InChI: InChI=1S/C97H126N20O32S/c1-49(2)39-68(114-95(147)71(43-54-46-101-60-18-11-9-16-57(54)60)116-97(149)73-19-12-37-117(73)75(120)48-103-85(137)58(98)24-30-76(121)122)93(145)110-65(29-35-81(131)132)91(143)109-64(28-34-80(129)130)90(142)108-63(27-33-79(127)128)89(141)107-62(26-32-78(125)126)88(140)106-61(25-31-77(123)124)87(139)104-50(3)84(136)113-69(41-52-20-22-55(118)23-21-52)86(138)102-47-74(119)105-70(42-53-45-100-59-17-10-8-15-56(53)59)94(146)111-66(36-38-150-4)92(144)115-72(44-82(133)134)96(148)112-67(83(99)135)40-51-13-6-5-7-14-51/h5-11,13-18,20-23,45-46,49-50,58,61-73,100-101,118H,12,19,24-44,47-48,98H2,1-4H3,(H2,99,135)(H,102,138)(H,103,137)(H,104,139)(H,105,119)(H,106,140)(H,107,141)(H,108,142)(H,109,143)(H,110,145)(H,111,146)(H,112,148)(H,113,136)(H,114,147)(H,115,144)(H,116,149)(H,121,122)(H,123,124)(H,125,126)(H,127,128)(H,129,130)(H,131,132)(H,133,134)/t50-,58+,61-,62-,63-,64+,65+,66-,67-,68+,69-,70-,71+,72-,73+/m1/s1

Notes unverified prose

Diagnostic use (gastric acid secretion testing); pentagastrin is synthetic analog; Pentagastrin diagnostic use

Not on file 0

All 8 tracked fields hold a value on this record: molecular weight and formula, CAS number, PubChem CID, amino-acid sequence, SMILES, InChI and InChI key.

Counted from the record itself, not from what a source said it was missing. 136 of 185 records still have at least one empty.