Tissue Repair & Regeneration
GHK-Cu
A copper peptide signal for skin, collagen, and remodeling research.
Last updated
Mechanism
Up-regulates collagen/elastin signaling and down-modulates MMP activity.
Reported effects
What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.
- Skin remodeling
- Scar quality
- Hair support
Dosing on file unverified
1-2.5 mg 3x/week, cycled 6–8 weeks
| Reported dose | Volume | Draw |
|---|---|---|
| Low — 1 mg | 0.2 mL | 20 units |
| High — 2.5 mg | 0.5 mL | 50 units |
What that assumes. Assumes 10 mg in 2 mL (5000 mcg/mL) drawn on a U-100 barrel — the preset on this record, not a recommendation and not the only way to mix it. Change the vial mass, the diluent or the barrel and every number in this table changes. Run your own.
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Reconstitution
| Vial | Diluent | Concentration | Typical dose | Draw |
|---|---|---|---|---|
| 10 mg | 2 mL | 5000 mcg/mL | 1000 mcg | 20 units |
mass ÷ diluent = concentration; dose ÷ concentration = volume; volume × the syringe factor = units on the barrel (100 for U-100, 40 for U-40). Run your own numbers.
Reported adverse effects
-
Injection site irritation
-
Copper accumulation with prolonged high-dose use
Literature on file 1
-
human RCT
NCT07437586: A Phase 2, Randomized, Double-Blind, Vehicle-Controlled, Split-Wound Study of Topical GHK-Cu (Copper(II)-Peptide Complex) Gel to Accelerate Re-Epithelialization of Standardized Acute Skin Wounds in Healthy Adults graded on: randomised and double-blind — “Randomized, Double-Blind”
Identity
Skeletal formulathe canonical depiction
Drawn by PubChem from CID 71587328, the identifier on this record.
- Molecular weight
- 402.92
- Molecular formula
- C14H23CuN6O4+
- CAS number
- 89030-95-5
- PubChem CID
- 71587328
- InChI key
- NZWIFMYRRCMYMN-ACMTZBLWSA-M
- Sequence
- GHK
- SMILES
- C1=C(NC=N1)C[C@@H](C(=O)N[C@@H](CCCCN)C(=O)[O-])NC(=O)CN.[Cu+2]
- InChI
- InChI=1S/C14H24N6O4.Cu/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);/q;+2/p-1/t10-,11-;/m0./s1
Classified as
- Subcutaneousroute
- This is the route the reconstitution arithmetic assumes. Mass divided by diluent volume gives concentration, dose divided by concentration gives volume, and volume in mL multiplied by 100 gives units on a U-100 barrel: 5 mg in 2 mL is 2.5 mg/mL, and 0.25 mg comes out at 0.1 mL, which is 10 units.
- Topicalroute
- Cosmetic records state a percentage in the jar. That is a concentration in the vehicle, not an amount delivered to living tissue, and the two are kept apart deliberately here.
Also called
- GHK-Cu
Notes unverified prose
Topical RCTs: Leyden et al. 2002 (67 women, 12 weeks); Phase 2; NCT07437586; injectable has no published RCTs; NCT07437586 (topical wound healing); Leyden 2002 RCT
Not on file 0
All 8 tracked fields hold a value on this record: molecular weight and formula, CAS number, PubChem CID, amino-acid sequence, SMILES, InChI and InChI key.
Counted from the record itself, not from what a source said it was missing. 136 of 185 records still have at least one empty.
Listed prices 36
What 34 shops we track listed for GHK-Cu, read from their own public catalogues on 2026-08-12. We take no commission on these and they are not ranked by any payment — how vendors are scored.
| Vendor | Size | Price | Per mg |
|---|---|---|---|
| PeptideProCanada | 100 mg | $55.00 CAD |
$0.55/mg |
| Great Northern Peptides | 100 mg | $65.00 CAD | $0.65/mg |
| Nox Peptides | 50 mg | $34.99 CAD | $0.70/mg |
| The Peptide Labs | 50 mg | $40.00 CAD | $0.80/mg |
| BioPerform | 50 mg | $44.99 CAD | $0.90/mg |
| Revico Labs | 100 mg | $90.00 CAD | $0.90/mg |
| Panda Peptide | 50 mg | $49.99 CAD | $1.00/mg |
| ExoLabz | 100 mg | $104.99 CAD | $1.05/mg |
| Ronin Peptides | 50 mg | $54.99 CAD | $1.10/mg |
| Maple Research Labs | 50 mg | $55.00 CAD | $1.10/mg |
| Northern Peptides | 50 mg | $55.00 CAD | $1.10/mg |
| Pacific Peptides | 100 mg | $110.00 CAD | $1.10/mg |
| Black Helix Labs | 50 mg | $60.00 CAD | $1.20/mg |
| Pacific Peptides | 50 mg | $60.00 CAD | $1.20/mg |
| Core Peptides Canada | 50 mg | $71.51 CAD | $1.43/mg |
| Canada Peptide | size not listed | $39.99 CAD | — |
| Maple Leaf Peptides | size not listed | $44.95 CAD | — |
| Polar Peptides | size not listed | $49.99 CAD | — |
| Researched Peptides | size not listed | $59.99 CAD | — |
| NCRP Canada | size not listed | $75.00 CAD | — |
| Vendor | Size | Price | Per mg |
|---|---|---|---|
| Zenith Biopeptides | 100 mg | $49.00 USD | $0.49/mg |
| Verified Peptides | 100 mg | $49.99 USD | $0.50/mg |
| AminoVault | 100 mg | $71.40 USD |
$0.71/mg |
| Ascension Peptides | 100 mg | $85.00 USD |
$0.85/mg |
| Core Peptides | 50 mg | $58.00 USD |
$1.16/mg |
| ResearchChemical.com | 50 mg | $59.99 USD | $1.20/mg |
| Biotech Peptides | 50 mg | $64.00 USD | $1.28/mg |
| Peptide Partners | 100 mg | $150.00 USD |
$1.50/mg |
| BioLongevity Labs | 50 mg | $84.97 USD | $1.70/mg |
| Wells Pharmacy Network | size not listed | $0.00 USD | — |
| Wells Pharmacy Network | size not listed | $0.00 USD | — |
| Coastal Peptides | size not listed | $48.00 USD |
— |
| Luxara Labs | size not listed | $48.75 USD | — |
| Protide Health | size not listed | $55.00 USD | — |
| Apex Peptides | size not listed | $98.00 USD | — |
| Vendor | Size | Price | Per mg |
|---|---|---|---|
| The Peptide CA | 50 mg | 49.00 (currency not stated) |
None of these shops lists your destination. Choose “Show all” to see every listing we hold.
Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.
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