Longevity & Cellular Health

Glutathione

A foundational redox and detoxification support molecule.

Last updated 12 August 2026

Studied forOxidative-stress support · Detox substrate · Mitochondrial function

Evidence on file2 randomised human trials · 3 human observational studies · 6 citations not yet graded

Strongest sourceNCT02311907: The Use of Glutathione (GSH) for Prevention of Paclitaxel/Carboplatin (TAXOL/CBDCA) Induced Peri… (randomised human trial)

Mechanism

Tripeptide redox buffer with NADPH-dependent recycling and phase-2 conjugation roles.

Reported effects

What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.

Oxidative-stress support
Detox substrate
Mitochondrial function

Dosing on file unverified

200-600 mg 3x/week, cycled 4–12 weeks

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 11

human RCT
NCT02311907: The Use of Glutathione (GSH) for Prevention of Paclitaxel/Carboplatin (TAXOL/CBDCA) Induced Peripheral Neuropathy: A Phase III Randomized, Double-Blind Placebo Controlled Study graded on: a randomised study — “Randomized, Double-Blind Placebo Controlled Study”
human observational
NCT02251041: Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL): a First-in-men Study graded on: a registered clinical study — “clinicaltrials.gov”
human RCT
NCT03020719: A Multi Center Placebo Controlled Double Blind Randomized Study Evaluating the Role of Oral Glutathione on Growth Parameters in Children With Cystic Fibrosis graded on: a randomised study — “Randomized Study”
human observational
NCT01402570: Oral Glutathione and Health Outcomes Among Persons With Post-Polio Syndrome graded on: a registered clinical study — “clinicaltrials.gov”
human observational
NCT02029521: Supplementation of Oral Reduced Glutathione in Pediatric Cystic Fibrosis for Growth Failure graded on: a registered clinical study — “clinicaltrials.gov”

Not graded

6 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

Space-filling 3D model of Glutathione, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Glutathione — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 307.33
Molecular formula: C10H17N3O6S
CAS number: 70-18-8
PubChem CID: 124886
ChEMBL: CHEMBL1543
InChI key: RWSXRVCMGQZWBV-WDSKDSINSA-N
SMILES: C(CC(=O)N[C@@H](CS)C(=O)NCC(=O)O)[C@@H](C(=O)O)N
InChI: InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1

Also called

Glutathione (GSH)

Notes unverified prose

Multiple clinical studies; skin lightening: 600 mg weekly x10; Parkinson's: 1,400 mg 3x/week

Not on file 1

1 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

amino-acid sequencenot applicable to this compound

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.

Listed prices 2

What 2 shops we track listed for Glutathione, read from their own public catalogues on 2026-08-12. We take no commission on these and they are not ranked by any payment — how vendors are scored.

Listed in CAD
Vendor	Size	Price	Per mg
Red Leaf Research Labs	1500 mg	$59.99 CAD ~~$70.00 CAD~~	$0.04/mg

Listed in USD
Vendor	Size	Price	Per mg
South Lake Pharmacy	size not listed	$0.00 USD	—

Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.