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Growth Hormone & Performance

Hexarelin

Space-filling model of Hexarelin

Last updated

Evidence on file1 animal study · 1 in-vitro study · 4 citations not yet graded
Strongest sourceHexarelin promotes the survival of retinal ganglion cells after optic nerve transection. (animal study)

Dosing on file unverified

IV: 0.5-2.0 mcg/kg single dose; SC: 1.5 mcg/kg 2-3x/day; Intranasal: 40-60 mcg/kg TID

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 6

Not graded

4 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

PubChem CID 6918297 computed 3D conformer Space-filling 3D model of Hexarelin, carbon grey, nitrogen blue, oxygen red
Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is one computed low-energy pose, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.
Skeletal formulathe canonical depiction
2D chemical structure of Hexarelin

Drawn by PubChem from CID 6918297, the identifier on this record.

Molecular weight
887.0
Molecular formula
C47H58N12O6
CAS number
140703-51-1
PubChem CID
6918297
InChI key
RVWNMGKSNGWLOL-GIIHNPQRSA-N
Sequence
HXAWFK
SMILES
CC1=C(C2=CC=CC=C2N1)C[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CC6=CN=CN6)N
InChI
InChI=1S/C47H58N12O6/c1-27-34(33-15-7-9-17-37(33)54-27)23-41(58-44(62)35(49)22-31-25-51-26-53-31)45(63)55-28(2)43(61)57-40(21-30-24-52-36-16-8-6-14-32(30)36)47(65)59-39(20-29-12-4-3-5-13-29)46(64)56-38(42(50)60)18-10-11-19-48/h3-9,12-17,24-26,28,35,38-41,52,54H,10-11,18-23,48-49H2,1-2H3,(H2,50,60)(H,51,53)(H,55,63)(H,56,64)(H,57,61)(H,58,62)(H,59,65)/t28-,35-,38-,39+,40-,41+/m0/s1

Notes unverified prose

Human dose-response: 0.5, 1.0, 2.0 mcg/kg IV; Intranasal children: 40-60 mcg/kg TID; Phase I/II human trials; dose-finding: 0.5, 1.0, 2.0 mcg/kg IV

Not on file 0

All 8 tracked fields hold a value on this record: molecular weight and formula, CAS number, PubChem CID, amino-acid sequence, SMILES, InChI and InChI key.

Counted from the record itself, not from what a source said it was missing. 136 of 185 records still have at least one empty.

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Share card for Hexarelin: structure, evidence rung and sources on file
www.peptidecorpus.com/peptides/hexarelin