Cardiovascular & General
Irisin
Last updated
Dosing on file unverified
No irisin-based therapeutic has entered human clinical trials as of 2026; in vitro: 5-100 ng/mL
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Literature on file 11
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human observational
Serum Bone-, Muscle- and Fat- Derived Factors Sclerostin, Irisin and Leptin Show Different Correlations With Body Composition and Bone Mineral Density in Chinese Men With Obesity: A Cross-Sectional Study. graded on: an observational human design — “Cross-Sectional”
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animal in vivo
Irisin-treated microbiota restore blood-testis barrier integrity and spermatogenesis in chronically stressed rats. graded on: an animal model — “rats”
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human observational
NCT02204670: Exercise and Irisin Trial (EXIT): Prospective Cohort Study of the Determinants of the Metabolic Response to Exercise in Obese Adolescents graded on: an observational human design — “Cohort”
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human observational
NCT04133896: Circulating IL-6, Clusterin and Irisin in Obese Subjects With Different Grades of Obesity: Association With Insulin Resistance and Sexual Dimorphism graded on: a registered clinical study — “clinicaltrials.gov”
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human observational
NCT06416033: Serum Irisin Level In Leprosy Patients graded on: a registered clinical study — “clinicaltrials.gov”
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human observational
NCT06696599: Serum and Corporal Irisin Level and Its Correlation With Erectile Function in Diabetic Obese Patients graded on: a registered clinical study — “clinicaltrials.gov”
Not graded
5 citations whose study design could not be read from the title. Left ungraded rather than guessed at.
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Notes unverified prose
Endogenous myokine; no therapeutic dosing; no FDA approval; No human clinical trials; preclinical
Not on file 8
8 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.
- molecular weightnothing we hold supplies it
- molecular formulanothing we hold supplies it
- CAS registry numbernothing we hold supplies it
- PubChem identifiernothing we hold supplies it
- amino-acid sequencenothing we hold supplies it
- SMILES stringnothing we hold supplies it
- InChInothing we hold supplies it
- InChI keynothing we hold supplies it
Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.