Tissue Repair & Regeneration

Oligopeptide-34

Last updated 12 August 2026

Evidence on file1 human observational study · 1 animal study · 1 citation not yet graded

Strongest sourceAxillary Hyperpigmentation Treatment: A Systematic Review of the Literature. (human observational study)

Manufacturer’s claim vendor marketing

For a proprietary cosmetic ingredient the manufacturer is the originator — there is no upstream to defer to, and this is often the only description that exists. It is reproduced as an attributed claim, with the label its source gave it. It is not graded and it is not evidence — the graded studies are under Literature.

Vendor claim (SpecialChem/Caregen datasheet): "Skin lightening & brightening, sun protection, anti-aging active"; "Provides even skin tone, prevents photo-aging and aged spots"; "Significantly inhibits melanin synthesis on melanocyte cell line". ci.guide adds: "decreases melanin synthesis by down-regulation of TRP-1, TRP-2, MITF, and Tyrosinase". No n= or duration on fetched pages.

Manufacturer: Caregen
Sold as: CG-TGP2

Source page — nofollow, because a vendor link is a reference here, not an endorsement.

Dosing on file unverified

5% solution; mesotherapy with microneedling

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 3

human observational
Axillary Hyperpigmentation Treatment: A Systematic Review of the Literature. graded on: a synthesis of human studies — “Systematic Review”
animal in vivo
Cosmeceutical product consisting of biomimetic peptides: antiaging effects in vivo and in vitro. graded on: an animal model — “in vivo”

Not graded

1 citation whose study design could not be read from the title. Left ungraded rather than guessed at.

not graded
MANUFACTURER_DATA_ONLY

Identity

Space-filling 3D model of Oligopeptide-34, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Oligopeptide-34 — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 737.0
Molecular formula: C38H68N6O8
PubChem CID: 71435492
InChI key: JFSQSDAOQLNSQI-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCC(=O)NC(C(C)C)C(=O)NCC(=O)NC(C(C)C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NCC(=O)O
InChI: InChI=1S/C38H68N6O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-22-30(45)42-33(26(2)3)36(50)39-24-31(46)43-34(27(4)5)37(51)41-28(6)38(52)44-23-20-21-29(44)35(49)40-25-32(47)48/h26-29,33-34H,7-25H2,1-6H3,(H,39,50)(H,40,49)(H,41,51)(H,42,45)(H,43,46)(H,47,48)

Also called

CG-TGP2
Oligopeptide-34

Notes unverified prose

Clinical study (n=22 Asian, 2x/day): pigmentation -47%; 6-month hair study (n=85, 5%): hair density +38.7 hairs/cm²; 6-month hair study (n=85, 5%): +38.7 hairs/cm²

Not on file 2

2 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

CAS registry numbernothing we hold supplies it
amino-acid sequencenothing we hold supplies it

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.