Cognitive & Neuroprotection
PEA
An oral fatty-acid amide for pain and inflammatory tone research.
Last updated
Mechanism
Influences PPAR-alpha activation, mast-cell ALIA signaling, and TRPV1 modulation.
Reported effects
What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.
- Chronic pain support
- Neuropathic pain support
- Gut-barrier modulation
Dosing on file unverified
300-600 mg BID, cycled 8–12 weeks
Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.
Literature on file 6
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human RCT
Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome. graded on: names a randomised controlled trial — “Randomised clinical trial”
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human RCT
Palmitoylethanolamide versus a nonsteroidal anti-inflammatory drug in the treatment of temporomandibular joint inflammatory pain. graded on: names a randomised controlled trial — the indexed publication type — “Randomized Controlled”
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human RCT
Palmitoylethanolamide (Levagen+) for acute menstrual pain: a randomized, crossover, double-blind, placebo-controlled trial. graded on: randomised and placebo-controlled — “randomized, crossover, double-blind, placebo-controlled”
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human RCT
Ultramicronized Palmitoylethanolamide and Luteolin Supplement Combined with Olfactory Training to Treat Post-COVID-19 Olfactory Impairment: A Multi-Center Double-Blinded Randomized Placebo- Controlled Clinical Trial. graded on: a randomised trial — “Randomized Placebo- Controlled Clinical Trial”
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human observational
Ultramicronized PEA (Normast) in Spinal Cord Injury Neuropathic Pain graded on: a registered clinical study — “clinicaltrials.gov”
Not graded
1 citation whose study design could not be read from the title. Left ungraded rather than guessed at.
- not graded
Identity
Also called
- PEA
Not on file 8
8 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.
- molecular weightno source on file holds this
- molecular formulano source on file holds this
- CAS registry numberthe reference database returned nothing for it
- PubChem identifierno source on file holds this
- amino-acid sequenceno source on file holds this
- SMILES stringthe reference database returned nothing for it
- InChIthe reference database returned nothing for it
- InChI keythe reference database returned nothing for it
Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.
Listed prices 1
What 1 shop we track listed for PEA, read from their own public catalogues on 2026-08-12. We take no commission on these and they are not ranked by any payment — how vendors are scored.
| Vendor | Size | Price | Per mg |
|---|---|---|---|
| Healthgevity | size not listed | 94.99 (currency not stated) | — |
None of these shops lists your destination. Choose “Show all” to see every listing we hold.
Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.