Longevity & Cellular Health

Tetrapeptide-30

Last updated 12 August 2026

Evidence on file1 computational study · 4 citations not yet graded

Strongest sourceUsage Frequency and Ecotoxicity of Skin Depigmenting Agents. (computational study)

Manufacturer’s claim vendor marketing

For a proprietary cosmetic ingredient the manufacturer is the originator — there is no upstream to defer to, and this is often the only description that exists. It is reproduced as an attributed claim, with the label its source gave it. It is not graded and it is not evidence — the graded studies are under Literature.

Vendor claim (SpecialChem/Evonik datasheet): "an anti-aging, anti-inflammatory and brightening agent" that "contributes to an even skin tone and leads to a visible fading of the hyperchromatic spots", "brightens the skin", "reduces acne lesions and alleviates melasma on ethnic skin". ci.guide adds it "helps to relieve melasma and/or post-inflammatory hyperpigmentation or acne lesions". No n= or duration on fetched pages.

Manufacturer: Evonik
Sold as: TEGO Pep 4-Even (TEGO Pep 4-Even MB)

Source page — nofollow, because a vendor link is a reference here, not an endorsement.

Dosing on file unverified

No established human dose; cosmetic serum concentrations vary

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 5

computational
Usage Frequency and Ecotoxicity of Skin Depigmenting Agents. graded on: a computational prediction — read from the indexed abstract — “in silico”

Not graded

4 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

not graded
MANUFACTURER_DATA_ONLY
not graded
Peptides: Emerging Candidates for the Prevention and Treatment of Skin Senescence: A Review.
not graded
Topical Treatments for Melasma and Their Mechanism of Action.
not graded
A framework for the safety evaluation of peptides in cosmetics.

Identity

Space-filling 3D model of Tetrapeptide-30, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Tetrapeptide-30 — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 500.6
Molecular formula: C22H40N6O7
CAS number: 1036207-61-0
PubChem CID: 25001762
InChI key: LYHZXMVNRVAAJA-QAETUUGQSA-N
SMILES: C1C[C@H](NC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)O
InChI: InChI=1S/C22H40N6O7/c23-11-3-1-6-15(26-19(31)14-8-5-13-25-14)20(32)27-16(9-10-18(29)30)21(33)28-17(22(34)35)7-2-4-12-24/h14-17,25H,1-13,23-24H2,(H,26,31)(H,27,32)(H,28,33)(H,29,30)(H,34,35)/t14-,15-,16-,17-/m0/s1

Also called

TEGO Pep 4-Even
Tetrapeptide-30

Notes unverified prose

Topical cosmetic studies only

Not on file 1

1 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

amino-acid sequencenothing we hold supplies it

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.