Tripeptide-29: dosing, sources and gaps

Manufacturer’s claim vendor marketing

For a proprietary cosmetic ingredient the manufacturer is the originator — there is no upstream to defer to, and this is often the only description that exists. It is reproduced as an attributed claim, with the label its source gave it. It is not graded and it is not evidence.

Vendor claims quoted from ci.guide: "significantly improves collagen synthesis, promoting wrinkle reduction, firming, and skin plumping"; improves "dermal-epidermal junction integrity and scaffolding matrix". No n= or study duration given on fetched pages.

Manufacturer: Active Concepts (per SpecialChem product listing); Apep Colla-5 by A&PEP
Sold as: AC Collagen Prepeptide PF (also Apep Colla-5 by A&PEP)
Manufacturer’s recommended use: Vendor claim: "0.1 - 1.0%"

Source page — nofollow, because a vendor link is a reference here, not an endorsement.

Dosing on file unverified

0.1% biomimetic collagen tripeptide; 4% CTP ampoule

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 1

Not graded

1 citation whose study design could not be read from the title. Left ungraded rather than guessed at.

not graded
MANUFACTURER_DATA_ONLY

Identity

Space-filling 3D model of Tripeptide-29, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Tripeptide-29 — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 285.30
Molecular formula: C12H19N3O5
CAS number: 2239-67-0
PubChem CID: 11778669
InChI key: SZEOBSAZWJLOGY-VGMNWLOBSA-N
SMILES: C1C[C@H](N(C1)C(=O)CN)C(=O)N2C[C@@H](C[C@H]2C(=O)O)O
InChI: InChI=1S/C12H19N3O5/c13-5-10(17)14-3-1-2-8(14)11(18)15-6-7(16)4-9(15)12(19)20/h7-9,16H,1-6,13H2,(H,19,20)/t7-,8+,9+/m1/s1

Also called

AC Collagen Prepeptide PF
Tripeptide-29

Notes unverified prose

4-week study (n=47 women, 36-65, 0.1%): improved skin hydration, texture, wrinkles; 4-week study (n=22 Asian women, 4%): significant wrinkle improvement; 4-week topical study (n=22 Asian women)

Not on file 1

1 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

amino-acid sequencenothing we hold supplies it

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.

Tripeptide-29