Functional Category
GLP-1 Agonists
Last updated
Compounds that activate the receptor for glucagon-like peptide-1, a hormone the gut releases after eating. On this site the category is used broadly and includes molecules that hit GLP-1 alongside other receptors, such as GIP, glucagon or amylin, because in commerce and in search they are treated as one family. The category sits beneath Metabolic.
Why it matters here
These are among the few records on the site where a top-rung human randomised trial exists for the headline outcome, which makes the distance between the graded compounds and the unstudied analogues sold beside them unusually easy to see.
What it is not
Incretin and GLP-1 are not synonyms: incretin is the wider class of gut hormones that amplify insulin release after a meal, and GIP is the other main one, so a dual agonist is an incretin mimetic that is only half a GLP-1 drug. Membership here also says nothing about a compound's own evidence, since a licensed medicine and an untested research analogue can share this shelf at opposite ends of the ladder.
Also called
- glp-1
- glp1
- incretin
- glp-1 agonist
- incretin mimetic
Incretin mimetic is the pharmacological name for the class. GLP-1 on its own is used in shops and forums to mean both the natural hormone and any drug that imitates it, which are different things.
Where it sits
- Broader term
- Metabolic
Compounds carrying this term
None on file yet. This term is in the controlled vocabulary but no compound record currently uses it — which is a statement about our coverage, not about the term.