Longevity & Cellular Health

NAD+

A core cellular-energy cofactor for mitochondrial and repair research.

Last updated 12 August 2026

Studied forCellular energy · DNA-repair support · Mitochondrial function

Evidence on file1 animal study · 4 citations not yet graded

Strongest sourceNicotinamide Adenine Dinucleotide as a Potential Biomarker for Graft Viability During Normothermic Machine Pe… (animal study)

Mechanism

Universal cofactor supporting ATP production and sirtuin activity.

Reported effects

What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.

Cellular energy
DNA-repair support
Mitochondrial function

Dosing on file unverified

50-250 mg 2-3x/week, cycled 2–12 weeks

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 5

animal in vivo
Nicotinamide Adenine Dinucleotide as a Potential Biomarker for Graft Viability During Normothermic Machine Perfusion-An Ex Vivo Rodent Study. graded on: an animal model — “Rodent”

Not graded

4 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

Space-filling 3D model of NAD+, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of NAD+ — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 663.4
Molecular formula: C21H27N7O14P2
CAS number: 53-84-9
PubChem CID: 5892
InChI key: BAWFJGJZGIEFAR-NNYOXOHSSA-N
SMILES: C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N
InChI: InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1

Classified as

Mitochondrial Functionpathway: The phrase appears in a great deal of product copy but is measured very differently across studies, from oxygen consumption in cultured cells to exercise capacity in a person, and the rung a claim earns usually depends on which was actually done.

Also called

NAD+

Not on file 1

1 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

amino-acid sequenceno source on file holds this

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.

Listed prices 9

What 9 shops we track listed for NAD+, read from their own public catalogues on 2026-08-12. We take no commission on these and they are not ranked by any payment — how vendors are scored.

Listed in CAD
Vendor	Size	Price	Per mg
The Peptide Labs	500 mg	$45.00 CAD	$0.09/mg
BioPerform	500 mg	$74.99 CAD	$0.15/mg
ExoLabz	500 mg	$109.99 CAD	$0.22/mg
Maple Leaf Peptides	size not listed	$84.95 CAD	—
Researched Peptides	size not listed	$119.99 CAD	—

Listed in USD
Vendor	Size	Price	Per mg
Zenith Biopeptides	500 mg	$50.00 USD	$0.10/mg
Certified Peptides	500 mg	$68.00 USD	$0.14/mg
Coastal Peptides	size not listed	$75.00 USD ~~$80.00 USD~~	—

Currency not stated by the vendor — these are not compared with any priced row
Vendor	Size	Price	Per mg
Healthgevity	size not listed	109.99 (currency not stated)	—

Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.