Cognitive & Neuroprotection

Oxytocin

A bonding and autonomic-state signal for social-stress research.

Last updated 12 August 2026

Studied forAnxiety/social-context support · HPA recovery · Libido research

Evidence on file3 human observational studies · 2 citations not yet graded

Strongest sourceNCT04551482: Oxytocin as a Neuroendocrine Therapy for Obesity in Youth (human observational study)

Mechanism

OXTR agonism affecting threat processing, social salience, and autonomic tone.

Reported effects

What sources associate with this compound. Reported categories, not outcomes we have graded — each would need its own citation and rung.

Anxiety/social-context support
HPA recovery
Libido research

Dosing on file unverified

10-20 IU as needed

Carried from a source that labels it unverified, and reproduced with that label attached. A record of what is reported, not a recommendation. No citation on this page establishes it.

Literature on file 5

human observational
NCT04551482: Oxytocin as a Neuroendocrine Therapy for Obesity in Youth graded on: a registered clinical study — “clinicaltrials.gov”
human observational
NCT04789148: Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency - A Pilot Study graded on: a registered clinical study — “clinicaltrials.gov”
human observational
NCT03860233: Benefits of Oxytocin in OSA Patients Using CPAP graded on: a registered clinical study — “clinicaltrials.gov”

Not graded

2 citations whose study design could not be read from the title. Left ungraded rather than guessed at.

Identity

Space-filling 3D model of Oxytocin, carbon grey, nitrogen blue, oxygen red — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

2D chemical structure of Oxytocin — Built from the SMILES on this record — the atoms, bonds and stereochemistry are exact. The shape is **one computed low-energy pose**, not a measured structure: a flexible peptide in solution has no single conformation. The skeletal formula below claims connectivity and nothing more, which is what we actually know.

Molecular weight: 1007.2
Molecular formula: C43H66N12O12S2
CAS number: 50-56-6
PubChem CID: 439302
UniProt: P01178
InChI key: XNOPRXBHLZRZKH-DSZYJQQASA-N
SMILES: CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N1)CC2=CC=C(C=C2)O)N)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
InChI: InChI=1S/C43H66N12O12S2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64)/t22-,25-,26-,27-,28-,29-,30-,31-,35-/m0/s1

Classified as

Intranasalroute: A nasal device delivers a fixed volume per spray, so concentration rather than syringe volume sets the amount per spray, and a mass figure on a record is not usable until you know how many actuations it was divided across.

Also called

Oxytocin

Notes unverified prose

NCT04551482 (weight loss, 24 IU 4x/day, 12 weeks); NCT04789148 (vasopressin deficiency, 6-24 IU); NCT03860233 (OSA, 40 IU/night for 14 days); NCT04789148

Not on file 1

1 of the 8 fields we track hold nothing on this record, and each says why. A blank field is a bug; a named absence is a finding.

amino-acid sequenceno source on file holds this

Each field links to every other record missing the same thing. The full ledger holds 521 gaps across 136 records.

Listed prices 4

What 4 shops we track listed for Oxytocin, read from their own public catalogues on 2026-08-12. We take no commission on these and they are not ranked by any payment — how vendors are scored.

Listed in GBP
Vendor	Size	Price	Per mg
Pharma Lab Global Canada	size not listed	£16.64 GBP	—
Direct Peptides Canada	size not listed	£20.64 GBP	—
Direct Peptides USA	size not listed	£20.64 GBP	—

Listed in CAD
Vendor	Size	Price	Per mg
Peptide Shop Canada	10 mg	$33.50 CAD	$3.35/mg

Prices are the vendor's own listing, reproduced with the date we read it — never converted between currencies, and compared per milligram only where the vendor states the vial size.